The story takes place in Rokuyo-cho, the birthplace of the Rush Duel. One day, Yuhi Oudou and Yuamu Oudou, two elementary school siblings who run a UTS (Uchuzin Trouble Soudansho / Alien Trouble Consultation Office) to get rid of annoying aliens, discover a spaceship, and when they step into it, they find an alien named Yudias Belgyar (This spelling may not be correct), who comes from the faraway Belgyar Cluster. He has come to Earth in search of the Rush Duel, which is said to lead his friends to a new future after they were forced to leave their home planet, but he has no idea what the Rush Duel is. Yuhi decides to give him a hand, and challenges Yudias to a duel.
Alternative Titles: Yu☆Gi☆Oh!: Go Rush!!, Yuu Gi Ou: Go Rush!!, Yu-Gi-Oh!: Go Rush, 遊☆戯☆王ゴーラッシュ!!